Honestly their is not as much difference on maximum point blank range between the 2 as you would think. With todays scopes and range finders I think it is a mute point.
To me there is a noticeable step up in recoil and muzzle blast going from a 30-06 to a 300 win mag. I think the muzzle blast bothers me more than the recoil, but I personally don't care for it.
My rifles have transitioned from a 7mm Rem Mag to a 7x57, 30-06, and a 9.3x62. I think the 06 sized cases are a great combination of power and shootability. If I were picking one for everything, I would be happy with a 30-06. Bullets for every type game is readily available off the shelf and most people can shoot an 06 accurately.