A few individual deaths is not the issue, it is the aggregation of all human caused mortality that is the problem. I'll use the numbers from the NCDE Grizzly Bear Population Monitoring Team Annual Report from 2021 as I live and work within it and thus are more familiar with it than the GYE. This report projects 1,163 bears in the NCDE in 2023.
"Fifty-five known or probable grizzly bear mortalities were documented in the NCDE during 2021." A continuation of this trend with the addition of five or ten more females could jeopardize the population, state management efforts, and overall population effectiveness.
Based on the NCDE Subcommittee guidance, the maximum threshold for the number of independent female mortalities for 2021 was set at 24, and there were 18 documented total female mortalities of which 12 were independent bears. So maybe a little room on an annual basis.
Another threshold set by the subcommittee is that the annual survival rate for independent females must be at 0.93 or greater. "For the 6-year period 2016–2021, we estimated an annual survival rate of 0.93 (± 0.01 SE) for independent females within the DMA, which meets the minimum threshold rate of 0.93 (NCDE Subcommittee 2019)." And so the overall trend is a bit touchier with losses of independent females.
All of these mortalities from self defense, travel corridors, conflicts, etc. take away from potential hunting opportunities.