First trip.. I left Indiana on a Thursday night, got to Colorado Friday afternoon, scouted, shot a buck at 8 AM on Saturday (opener) and was home by Sunday afternoon.
Now I try to stretch my trips out longer. All that planning and anticipation, it's a shame when it's over in a flash like that.
Most trips I take one week, with a weekend on either side. Sometimes I do two weeks, like my Wyoming deer hunt coming up this year.
When my kids are older, I may burn all my PTO at once and go for a month. For now, I try to keep it to one trip per month from September-December, with an occasional spring bear hunt in May.