Sir, I can not over emphasize the importance of "fit". Weatherby, who is in your neck of the woods, makes a nice rifle--for women.
practice, practice, practice and not just for accuracy--she needs to know and feel comfortable shooting her rifle.
Dont start her off with something that is going to create a possible automatic flinch---start with a 22 and shoot it and shoot it and shoot it--ammo is cheap, and shooting a 22 can be good practice, even fun, and it needs to be fun.
A 243 is enough for deer and antelope, then maybe a 7mm-08 ( I also believe Weatherby makes one for women in the Creedmore, but since I have never owned one, I can not speak to that caliber )
If you get one of the European rifles made for women, I would then recommend the 6,5 x 55 and IMHO the Swede s an excellent caliber and more than enough for the animals she will be hunting.
Start with less, not more and as she gains comfort and confidence then get her a larger caliber, when she says ' I want to hunt moose and brown bear"