Have they attacked humans? Yes. Is it far and few, mostly though the incidents are increasing the more humans encroach
into apex territory. To the extent the government of Alaska shares the following:
Attached pdf of alaska.gov study referenced in their linked information above.
Many MT, ID, WY outdoors people have encountered wolves in one form or another.
I was less than 10 feet from one and didn't have an ounce of fear, to the extent I was trying to pull my phone from my chest bino pounch to record as we starred at each other. Right next to my bino pouch is my attached holster. Not a thought entered my mind to go for my gun.
I've also been archery hunting in/along the Saphire wilderness area with my hunt buddy and found ourselves surrounded by wolves howling/barking. That gave me the cold run up the spine.
Buddies hunting along Dixon - Thompson area north of Missoula found themselves surrounded by a pack of wolves as they were prepping an elk for packout. Fired shots which spooked them off a bit yet they returned.
They're tough sob hunters that are dedicated LEOs. Made their way, packed with elk, back to the truck a few miles away. Said it was flipping eerie as the wolves sounded off while they hiked out along a trail, unable to see except for the occasional catch of reflective eyes from their headlamps.
They always carry wolf tags now. Not for the interest to take wolves, but to shoot them without concern for administrative paid leave until determined if justified for shooting the farkers.
Long story summarized, I love solo hunting the Bob, Ten Lakes, Cabinets, Saphines, along with other wolf populated areas and have had my fair share of incidents far beyond what I shared above. I'm not overly concerned
though I do respect their capabilities.