I am probably one of, if not the biggest Hornady shooter you'll ever meet... I do, for most calibers believe in shooting heavier for caliber bullets, regardless of manufacturer... I agree, there are some good tough bullets out there, I'm a firm believer that if you are familiar with your firearm, and know it well, that any bullet will do the job nicely...
Myself, I've been shooting the Hornady A-Max's in everything I shoot... And I'm a firm believer in them... A couple of years ago I shot this whitetail buck stem to stern from just shy of 300 yds with my 6.5x284 with a 140gr A-MaxI took him just below the throat patch, and I found it in the left hind quarter when I skinned it to cut him up at home...
And here's the recovered bullet @ 53% retention:
The week after I took this buck, I took this spike bull in area 339 just behind my house from 500 yds with a high shoulder shot, dropping him like a sack of rocks, and passing completely through... Not a big whopper bull, but still elk nonetheless....
I would like to see you shoot a 180gr SST in that '06, especially if it's a hunt of a lifetime, I think the 150 is a bit light if you were to have a marginal shot, but should work fine if you have a perfect broadside shot... I shoot the 180gr SST in my 308 @ 2630 fps and it shoots awesome groups, and will completely penetrate anything I shoot with it... If you're comfortable with your '06, Hornady makes a Superformance load with the 180 SST or 180 Interbonds @ over 2800 fps. Try those out, you won't be disappointed...
Oh, and good luck...