Honestly, most modern guns can deal with excess pressure just fine. There are only really 2 ways to blow up guns/actions reliably:
1. Occlude the barrel somehow. Mud, 20 ga in a 12 ga, etc.
2. Use a radically wrong powder. Usually this is pistol powder in a rifle cartridge. H110 instead of H1000 and you are pulling the trigger on a pipe bomb....
It's not just the gun blowing up. It's the wear and tear on an action and bbl through excessive pressure, shorterning the life of the firearm and/or creating excessive headspace issues over time. You're also looking at other issues like pierced primers, increased potential for case-head separation, etc. The rush to increase velocity in existing cartridges just seems like a marketing-driven desire to get more of your money more than aything else.
The PRC family, as a comparison, was designed for the rifles they're going in - longer throats, chambered specifically for the cartridge. Those guns will all have shorter barrel life, but because they using brass cartridges, you'll likely see the problems faster if you handload/reload (loose primer pockets, incipient casehead sep, etc).
