I've had a 5th wheel for quite a while and (knock on wood) have never had any issues. Mine is not a toy hauler, it's 32'. I have the larger 235/85R16 tires that are 14 ply. I welded a hitch on the back myself and used heavy duty materials. I tow a couple ATV's on a trailer, and I also have a 17' Crestliner boat that I pull around. I would never go back to a bumper pull after having a 5th wheel.
My truck is a 2019 GMC 2500HD Diesel, which I think is pretty similar to yours. It has plenty of power to tow my stuff faster than I should, so I am very conscience about keeping it safe. We have some elk tags in Wyoming this year and I will be towing this setup there in October.
If you decide to go with a 5th wheel I have no doubt you will be glad you did.
One other note. I have an Anderson Hitch that's rated for 24,000lbs. It attaches to my B&W turn over ball. It's all aluminum and I can lift it in and out of the truck easily.
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