I think what was suggested is pretty spot on about figuring out what bullet you want FIRST, then deciding on cartridge to make that bullet perform.
If you want to shoot mono's for example, I would bypass any of the lower velocity rounds like the 6.5 CM, 7-08, and even 308, 30/06 too. Anything under about 2800 FPS is going to give you fits with mono's. There's been threads about that on hunttalk that resulted in animals not being found right away due to crap expansion. The mono's need something with some ass behind them, really can't be pushed too fast.
Twist rate is also a consideration depending on if you want heavy for caliber or more standard fare for bullet weight.
I'll give you some first hand experience, when I had 2 7-08's built, I knew I was going to be shooting the 140 grain accubonds or BT's. I twisted 1-9, way more than plenty for a 140, magazine length even in short actions was not a problem, yada yada. I had ZERO intention of ever shooting mono's in those 2 rifles, and I don't. I get 2850-2910 for velocity, plenty for a 140 cup and core/bonded, but not too much either. I would argue a pretty sweet spot and a mountain of dead animals seem to be the proof. I won't be shooting mono's in either one, ever (unless forced by law).
If I were to make the move to mono's in the .284 I'd do it in my 7RM and push them as fast as I could. Out of a requirement I did load some mono's for my 7RM, 140 E-tips, for that rifle and they shoot fantastic. Even at 3200 FPS and the label on the box claiming they expand fine at slower velocities, I have to holler BS on the label. I shot a dozen or so animals with them, including some largish bull elk and a bull moose. Lets just say I'm glad I didn't have to shoot anything past 350ish yards with them. Expansion was pretty lame on those bullets and I recovered a couple, even at 3200 FPS from the muzzle.
What most hunters would be wise to do is give things more than a passing thought on what they want out of the bullet and select a cartridge accordingly.
But, no matter how much you try to help, most are going to ignore the logic and then get pissed when they can't find an elk for a day or two after they shot it. Of course, its not THEIR fault, its the cartridge.