I'm having to eat some serious crow on the 7mm RM...Bambistew and I went round and round on it a while back. He was right, I was wrong. The 7mm hunts/kills bigger than the caliber, and thats just a simple fact.
Unless you're in need of killing mostly larger big-game...I'd have to say go 7mm. Even then, the more I hunt, the more I believe that speed, "knock down power" and all that other BS are wayyyy over-rated. I still have a soft spot for 30's and 338's for elk, but, IMO, shot placement and bullet construction are much more important.
A well placed bullet of proper construction makes many garden variety standard calibers kill way better than they seem like they should.
As to bullet weight, I'd stick with 160's in the 7mm...and I'd give the accu-bonds a good close look for sure. I tried them in mine this spring and the results were pretty impressive on paper, 300 yard 3-shot group:
I was concerned with them on game...but got over that real quick, killed 10 big-game animals with them this year:
The second and third bullets from the left are from the bull I just killed in AZ...620 yards and were recovered on the off-side. The farthest right bullet from a mule deer buck shot stem-to-stern at about 130 yards. Not sure how any bullet could perform much better.
Good luck with your decision.
Heres my rifle rem 700 bdl, factory barrel 24 inches, B&C Ti stock, timney trigger at 2.75#, m-1 turrets on a 3x9 leupold with a leupold dot reticle, bedded and floated, talley LW rings and bases, Montana sling...