Initial data actually did not show much muscle or bone density difference with GLP-1 use from what I’ve read. However, I was at an orthopedic conference this spring and there was some concerning trends starting to show.
Weight Loss Drugs
- Thread starter Elky Welky
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Initial data actually did not show much muscle or bone density difference with GLP-1 use from what I’ve read. However, I was at an orthopedic conference this spring and there was some concerning trends starting to show.
Hams42
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A not accurate scale. I take it with a grain of salt. I definitely feel weaker than when I was 280 lbs but still have the majority of my muscle at 205 lbs.
Hams42
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I assume just a lack of vitamins and minerals from lower food intake?
I may be a outlier but I have still roughly tracked my food intake over the course of time I've been on the drug. I also waited for quite a while before upping my dosage to the next step. This caused me to loose weight slower but I think it was better that way.
Do you think it was directly from the glp-1 or simply from not eating enough to maintain the muscle? You can lift all you want but if you can’t eat enough calories your body won’t maintain muscle.
This is true. Broadly speaking the physics don't differ between people.
Though, there are people like myself who can't really gain weight even if we try. lucky problem i know. I don't have any special willpower other folks lack, and really, if we're honest, I probably have less willpower than most people.
The thing people often overlook is that my inability to gain weight is no different than other people's inability to lose it. The physics are the same, if I ate more, I would gain weight, my body is not special in that regard, whereas if others ate less, they would lose weight, their body's are similarly not special in that regard. But the hormonal balances in our bodies that tell us to eat more or less after given inputs are inherently different and we largely have little control over how that dice roll lands in our genetics. Neither one of us can fight those signals any better than the other. My body tells me to stop eating so I stop when another dudes body screams at him to keep eating. To do the opposite is fighting hormonal signals telling our brains to tell our bodies to do what it thinks our bodies should be doing, overpowering that is not easy. My body forces me in one direction and theirs another.
I just hope more people realize that many folks inability to lose weight is not a result of their lack of willpower.
I'm largely agnostic on the drugs. Proper use of medicine is life changing and I want people to leverage everything they can to live fulfilling lives.
But I do fear that because history shows us in the world of bodily health that easy buttons often come with consequences, we may be getting a little loosey goosey with the access to these things. I hope not. But it is certainly the open ended question nobody can definitely say here with the GLP-1s.
Hams42
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I think it was from just losing weight. You can't strictly just loose fat you are bound to loose muscle as well. You can do your best to offset it by lifting and keeping a high protien intake but you can't stop it completely.
sclancy27
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This is largely BS. If this was the case we would have had generations of society with the inability to lose weight. Phenotype = Genotype and genes don't change that degree over the equivalent of a human generation.
Two things were largely at play; 1). Food became much easier to procure and "food scientists" produced food that we can eat more of without feeling full. 2). The vast majority of society rapidly transitioned from labor-focused jobs to sitting in a chair for work. Reason #2 probably had a greater effect than reason #1.
There are people who have true hormonal issues but they are the vast minority.
That is my assumption, but I haven't seen evidence supporting it. That explanation does makes sense intuitively.
the genes were always there. a changing society and a changing food supply acted as combo multipliers on the effects those genes can have.
autistic kids were just as autistic in 1700 as they are now. people just didn't know what their deal was so they were just weird kids. put those same kids in a modern screen fueled time stressed society and all of the sudden you have a very novel and acute problem that never existed before, even if the spectrum disorder is technically identical.
sclancy27
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Look at studies of natural bodybuilders, they lose lean mass too, especially as the cumulative weight loss gets larger. Lean mass loss is symptom of significant weight loss. You can minimize it by weight training HARD, but it is still going to happen.
The reason I was interested in DEXA results is that puts "lean mass" into actually categories; bone, muscle, water, etc. Without that context "lean mass" is a pretty worthless term.
Hams42
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From things I have seen even the DEXA's can be wildly inaccurate.
sclancy27
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DEXA is the gold standard for body comp.
Hams42
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I know im just saying that there have been some wild readings that body builders have gotten specificly on their body fat percentage. Marking them lower then they truly are.
They can be the gold standard and still have issues.
sclancy27
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You are talking about 1-2% error for people who actually know how to use the machine. It's also used for tracking osteopenia/osteoporosis in a clinical setting.
I can't speak for people running it that don't know what they are doing.
