The kids and I have had great luck with the TTSX on deer, antelope and elk. We load them for:
300 H&H
30'06
280 AI
7x57
.270
.243
accurate in all and deadly thus far.
I hunted in Wyoming with a guy who used a 257 Weatherby on prairie goats and a muley with 115 grn TSX , man was that thing devastating on animals, muley was 340 yards, freakin awesome gun/bullet combo !!